Spatial Insights Driving Drug Discovery

A webinar series exploring the impact of spatial biology from early-stage discovery to the clinic

 

Advancements in spatial biology and its transformative impact on drug discovery

Join us to explore the groundbreaking advancements in spatial biology and its transformative impact on drug discovery. This series brings together leading experts to share insights on how spatial biology is reshaping our understanding of complex biological systems, optimizing therapeutic development, and advancing precision medicine from the lab to the clinic

What to expect: 
  • Insights from top experts at the intersection of spatial biology and drug discovery.
  • Practical applications of spatial biology techniques in early-stage and clinical drug development.
  • Case studies showcasing real-world impact and breakthroughs.
  • A closer look at how spatial technologies are unlocking new avenues for precision medicine
  • Opportunities for interactive Q&A with leading scientists and researchers.

This series promises to be an invaluable resource for anyone interested in the future of drug discovery and the exciting role spatial biology will play in it. Don’t miss the chance to stay ahead of the curve in this rapidly evolving field!

 
Expert Speakers: 

The Evolution of Multiplexing: Enhancing ADC and Immuno-Oncology Therapy Selection

Date: Thursday, 15th May 2025 

Time: 9am PDT | 12PM EDT | 6PM CEST 

Speaker: Mark Landers, VP of Precision Medicine, Akoya Biosciences

Join this webinar to hear Mark Landers, VP of Precision Medicine at Akoya Biosciences explain how multiplexing technology has evolved from research to a critical tool in clinical programs, integrating advanced staining reagents, digital quantification, and precise controls. Learn how this advancement is essential for the development of targeted ADC and Immuno-Oncology therapies, improving clinical trial outcomes and patient care by enabling more accurate biomarker analysis and patient selection.

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A Spatial Multi-omics Approach to Decipher Tissue Biology for Drug Discovery

Date: Thursday, 29th May 2025 

Time: 9am PDT | 12PM EDT | 6PM CEST 

Speaker: Clément Levin PhD, Senior Principal Scientist, Sanofi

In digital pathology, technologies like multiplex immunofluorescence and spatial transcriptomics enable in-depth analysis of tissue samples. In this webinar Clément Levin PhD, from Sanofi describes a study combining 34-protein PhenoCycler panel with Visium transcriptome analysis on head and neck squamous cell carcinoma. This approach uncovers immune phenotypes, cancer cell states, and gene-protein expression comparisons within spatially resolved subspaces

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Tertiary Lymphoid Structures in Cancer Immunotherapy: Insights and Perspectives

Date: Thursday, 12th June 2025 

Time: 9am PDT | 12PM EDT | 6PM CEST 

Speaker: Professor Antoine Italiano, Head of the Early Phase Clinical Trials, Institut Bergonié, Bordeaux, France 

Tertiary lymphoid structures (TLS) play a key role in the tumor microenvironment, affecting immune responses and cancer outcomes. Professor Antoine Italiano will present recent advancements in TLS research, particularly in soft-tissue sarcomas, and discusses their potential as biomarkers for immunotherapy response. Key findings from the PEMBROSARC trial and ongoing research will be highlighted.

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Spatial Awareness: AI-powered Profiling of Trillions of Immune Cell Distribution Data Points Reveals Key Predictors of Cancer Recurrence Risk

Date: Thursday, 26th June 2025 

Time: 9am PDT | 12PM EDT | 6PM CEST 

Speaker: Dr. Joe Yeong Poh Sheng (MBBS, PhD), Group Leader, Institute of Molecular and Cell Biology 

In the age of AI and big data, extracting meaningful biological insights requires more than just computational power—it demands strategic design. In this webinar, Dr. Joe Yeong Poh Sheng will present a groundbreaking study (Nature cover story, April 2025) demonstrating how a pre-designed analytical framework guided by clinical questions enabled interpretation of over a trillion spatial data points across 300 patients. The study integrated multi-tissue, multi-modal data—spanning gene and protein expression, cellular phenotypes, and clinical parameters. Dr. Yeong Poh Sheng will also introduce a novel, AI-driven clinical scoring system, validated through spatial proteomics, that sets the stage for a new era in spatial medicine.

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